Intrauterine insemination (IUI) is one of the first fertility treatment options recommended for many patients. While IUI is less complex and less expensive than IVF (around $1,200-$4,000 per cycle without insurance), it still involves medications, monitoring, and specialized lab work.
With insurance, this amount is often significantly lower. Your final out of pocket cost depends on your diagnosis, insurance benefits, and treatment plan.
This page provides a clear breakdown of self-pay and insured IUI costs, what influences pricing, and how Illume Fertility supports you through the financial side of treatment.
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Disclaimer: The information on this page is for general educational purposes only. All price ranges and examples are estimates and do not constitute guaranteed rates, promises of coverage, or a reflection of Illume Fertility’s current pricing or fees. Actual costs vary based on your insurance plan, pharmacy pricing, medical needs, and the treatment plan recommended by your provider. Illume Fertility’s Financial Coordinators will review your specific benefits and provide an individualized cost estimate after your consultation. Pricing, accepted insurers, and program availability are subject to change.
For patients who are uninsured or whose plans exclude IUI, a typical cycle ranges from $1,200 to $4,000+ per cycle depending on medication needs, monitoring, and whether donor sperm is used.
Patients with insurance often pay significantly less, typically $300 to $1,000+ per cycle after deductible and coinsurance.
Your geographic location, choice of fertility clinic, add-on services (such as donor sperm), the complexity of your case, and other factors also influence the amount you pay for your IUI journey.
To view detailed IUI cost breakdowns, select your path:
I Have Insurance I'm Self-Pay
Because every IUI journey is personalized, the cost of treatment can vary widely. The main factors influencing your total amount include:
If IUI is covered, your plan's deductible, copay, and related costs are the main factors. Without coverage, out-of-pocket costs increase.
Some patients respond quickly; others require more attempts. Your physician will help you estimate likelihood of success and whether moving to a higher-intervention path (like IVF) may be more efficient.
Whether you are doing a natural cycle, oral medications (Clomid/Letrozole), or injectables significantly changes cost.
If using donor sperm, additional costs (such as genetic or psychological counseling, vial shipping, and storage) will apply.
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The following price ranges are based on aggregated national data from ASRM, FertilityIQ and leading fertility clinics. Figures reflect published national averages and do not guarantee individual pricing at Illume Fertility.
Typical price ranges for patients who are uninsured or lack coverage for IUI.
May involve bloodwork, imaging, infectious disease screening, and semen analysis, depending on which tests your provider orders during the evaluation process.
Includes oral medications, injectable gonadotropins when needed, and an optional trigger shot, with costs varying based on your personal treatment plan.
Includes cycle monitoring, bloodwork, and ultrasounds needed to track follicle growth, confirm ovulation timing, and prepare for the insemination procedure.
Covers in-office insemination performed with a prepared sperm sample, precisely timed with ovulation to help increase the chance of sperm reaching the egg.
Annual cryobank or clinic storage for frozen sperm, with costs varying based on storage duration, location, and quantity of vials being stored.
For patients utilizing donor sperm
Same-sex female couples, single mothers by choice, and individuals or couples with male factor infertility or heritable genetic conditions often use donor sperm for IUI. Below is a breakdown of common costs associated with this donor conception path.
Cryobanks offer different vial types specifically prepared for insemination. For IUI, washed vials are most commonly used, but your Care Team will confirm the appropriate type for your treatment plan.
For IUI, sperm thaw and preparation (sperm washing) may be billed separately, typically ranging $150 to $350 per cycle depending on the sample and processing method. Often covered by insurance.
Recommended or required for reviewing donor carrier screening, assessing compatibility with the recipient’s genetics, and understanding potential implications for offspring. Typical costs range from $150 to $400+, depending on insurance coverage.
Frequently recommended or required for patients pursuing donor conception. Sessions focus on emotional readiness, future disclosure conversations, and family-building dynamics. Fees generally range $175 to $350+ per session and may be covered by insurance.
Not typically required for donor sperm purchased through a licensed cryobank. However, legal guidance may be recommended in known donor arrangements or for certain family structures. Fees range from $500 to $2,000+, depending on the attorney.
Many cryobanks require a subscription to access extended donor details, such as adult photos, genetic test results, or audio interviews. Subscription fees usually range $100 to $400+.
Typical price ranges for insured patients with IUI coverage.
Most insurance plans cover initial fertility testing as diagnostic care, though patient costs vary based on lab copays, network status, and other factors.
Out-of-pocket costs depend on your plan’s coverage for monitoring, labs, and specialist visits; influenced by deductibles, copays, and whether services are billed in or out of network.
Costs depend on whether your plan covers oral ovulation drugs, trigger shots, or injectables, with pricing influenced by tier placement, specialty pharmacy requirements, and deductibles.
Dependent on how your plan covers the insemination procedure, with patient responsibility determined by visit copays, coinsurance percentage, and remaining deductible balance for the year.
Long-term storage for frozen sperm is typically an out-of-pocket cost, with yearly fees depending on the storage facility and whether multiple vials are being preserved for future cycles.
At-home insemination can seem appealing because it feels more private, flexible, and affordable. But the differences between at-home insemination and monitored IUI cycles are significant and can impact safety, timing, and success rates.
At-home insemination:
By comparison, IUI cycles performed in a clinic offer expert medical guidance, precise timing, and direct placement of washed sperm into the uterus, which help support higher success rates and safer treatment. These elements are difficult to replicate outside a clinical setting.
At Illume, we prioritize clarity, safety, and evidence-based care, with each IUI cycle carefully planned and monitored to give you the strongest possible chance of conception.
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The top questions about costs associated with intrauterine insemination (IUI).
It depends! Coverage varies widely between plans. While many insurers cover the insemination procedure, monitoring, and medications, others cover only diagnostic testing or require patients to meet a definition of infertility before benefits apply.
Connecticut and New York both have state fertility mandates that require fully-insured, large group insurance plans to cover certain aspects of fertility treatment. However, not all employers are required to participate and may opt out, depending on the type of plan they offer.
Illume Fertility's knowledgeable Financial Coordinators will work alongside you to confirm your coverage details and ensure you feel informed from the very start.
A single IUI cycle usually costs $900 to $4,000+, depending on monitoring, medications, sperm washing, and whether donor sperm is required.
Natural cycle IUIs or cycles with oral medications fall on the lower cost end. Cycles using injectable gonadotropins or donor sperm are generally more expensive.
IUI has a wide cost range because several key components vary between patients, including medication type and dosage, number of monitoring visits, sperm processing needs, and whether donor sperm is required.
Some cycles are very simple, while others require more involved monitoring or higher-priced medications, which creates the variability.
At-home insemination may cost less upfront, but it does not include ultrasound monitoring, hormone testing, sperm washing, or precise timing, which can reduce success rates. Clinic-based IUI also places washed sperm directly into the uterus, which cannot be done at home.
For patients investing time and emotional energy into trying to conceive, monitored IUI offers higher accuracy and a stronger chance of success.
Many patients complete three to four cycles of IUI before moving on to IVF if pregnancy has not occurred. Success rates often accumulate over several cycles.
Your physician will tailor their recommendations and your treatment protocol based on age, diagnosis, hormone levels, and sperm quality.
Three cycles of IUI typically cost $2,700 to $9,000+ out of pocket, depending on monitoring, medications, sperm washing, and whether donor sperm is used.
Most patients fall on the lower end if using oral medications and their partner's sperm. Costs increase when injectable medications or donor sperm are part of treatment.
IUI is often recommended for patients with unexplained infertility, mild male factor infertility, or cervical factor issues, as well as those utilizing donor sperm with IUI.
Basic requirements that determine eligibility for IUI: You must have at least one functioning fallopian tube, a normal uterine cavity, and an ovulatory cycle that can be monitored.
First-cycle IUI success rates are often around 10 to 20%, depending mostly on age and diagnosis. Patients under 35 with no major fertility issues tend to have higher success rates than patients with diminished ovarian reserve or significant sperm abnormalities.
IUI success rates are highest in people under 35, moderate between 35 and 38, and lower after 40 due to natural age-related changes in egg quality. Your provider will review your ovarian reserve testing to determine whether IUI is medically appropriate.
Not necessarily. IUI is less invasive and less expensive, but it also has lower per-cycle success rates than IVF.
For younger patients with unexplained infertility or mild male factor infertility, IUI is often an appropriate first step. For patients with more complex diagnoses, blocked fallopian tubes, low ovarian reserve, or advanced maternal age, IVF may offer a greater chance of a healthy pregnancy in fewer attempts.
It's no secret that fertility treatment can be expensive.
This helpful guide breaks down all of your options (including financing and clinic-based packages), offers budgeting tips, shows you how to maximize your insurance coverage, apply for grants, and much more.
Ready to take control of your fertility journey? Fill out the form and get instant access to your free Guide to Financial Planning for Fertility Treatment.
Explore our Learning Center to get educated on costs and ways to afford treatment.
Take the next step by scheduling your initial consultation with an Illume Fertility physician. After this consultation, your dedicated Financial Coordinator will review insurance and benefit details (if applicable), estimate expected testing and treatment costs, and answer your IUI cost questions.
When you're ready, Illume Fertility is here to help.
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